Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5)

[Image: see text] Protein arginine methyltransferase 5 (PRMT5) belongs to a family of enzymes that regulate the posttranslational modification of histones and other proteins via methylation of arginine. Methylation of histones is linked to an increase in transcription and regulates a manifold of fun...

詳細記述

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書誌詳細
出版年:ACS Med Chem Lett
主要な著者: Palte, Rachel L., Schneider, Sebastian E., Altman, Michael D., Hayes, Robert P., Kawamura, Shuhei, Lacey, Brian M., Mansueto, My Sam, Reutershan, Michael, Siliphaivanh, Phieng, Sondey, Christopher, Xu, Haiyan, Xu, Zangwei, Ye, Yingchun, Machacek, Michelle R.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2020
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7488283/
https://ncbi.nlm.nih.gov/pubmed/32944135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00525
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