Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression

BACKGROUND: Colorectal cancer (CRC) development is generally accepted as a sequential process, with genetic mutations determining phenotypic tumor progression. However, matching genetic profiles with histological transition requires the analyses of temporal samples from the same patient at key stage...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Mamlouk, Soulafa, Simon, Tincy, Tomás, Laura, Wedge, David C., Arnold, Alexander, Menne, Andrea, Horst, David, Capper, David, Morkel, Markus, Posada, David, Sers, Christine, Bläker, Hendrik
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487684/
https://ncbi.nlm.nih.gov/pubmed/32895052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-020-00844-x
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