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Alignment and mapping methodology influence transcript abundance estimation

BACKGROUND: The accuracy of transcript quantification using RNA-seq data depends on many factors, such as the choice of alignment or mapping method and the quantification model being adopted. While the choice of quantification model has been shown to be important, considerably less attention has bee...

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Vydáno v:Genome Biol
Hlavní autoři: Srivastava, Avi, Malik, Laraib, Sarkar, Hirak, Zakeri, Mohsen, Almodaresi, Fatemeh, Soneson, Charlotte, Love, Michael I., Kingsford, Carl, Patro, Rob
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487471/
https://ncbi.nlm.nih.gov/pubmed/32894187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02151-8
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