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Alignment and mapping methodology influence transcript abundance estimation

BACKGROUND: The accuracy of transcript quantification using RNA-seq data depends on many factors, such as the choice of alignment or mapping method and the quantification model being adopted. While the choice of quantification model has been shown to be important, considerably less attention has bee...

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Dettagli Bibliografici
Pubblicato in:Genome Biol
Autori principali: Srivastava, Avi, Malik, Laraib, Sarkar, Hirak, Zakeri, Mohsen, Almodaresi, Fatemeh, Soneson, Charlotte, Love, Michael I., Kingsford, Carl, Patro, Rob
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487471/
https://ncbi.nlm.nih.gov/pubmed/32894187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02151-8
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