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Alignment and mapping methodology influence transcript abundance estimation

BACKGROUND: The accuracy of transcript quantification using RNA-seq data depends on many factors, such as the choice of alignment or mapping method and the quantification model being adopted. While the choice of quantification model has been shown to be important, considerably less attention has bee...

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Bibliographische Detailangaben
Veröffentlicht in:Genome Biol
Hauptverfasser: Srivastava, Avi, Malik, Laraib, Sarkar, Hirak, Zakeri, Mohsen, Almodaresi, Fatemeh, Soneson, Charlotte, Love, Michael I., Kingsford, Carl, Patro, Rob
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487471/
https://ncbi.nlm.nih.gov/pubmed/32894187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-020-02151-8
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