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Tabersonine ameliorates osteoblast apoptosis in rats with dexamethasone-induced osteoporosis by regulating the Nrf2/ROS/Bax signalling pathway

We explored how tabersonine (Tab) protected against dexamethasone (Dex)-induced osteoporosis. Osteoblasts were treated with Dex (100 µM) with or without Table (5 or 10 µM). We measured cell viability, alkaline phosphatase (ALP) activity, and mitochondrial superoxide and reactive oxygen species level...

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Библиографические подробности
Опубликовано в: :AMB Express
Главные авторы: Sun, Xi, Gan, Lijun, Li, Nan, Sun, Shuyi, Li, Na
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486361/
https://ncbi.nlm.nih.gov/pubmed/32915329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-01098-0
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