Tabersonine ameliorates osteoblast apoptosis in rats with dexamethasone-induced osteoporosis by regulating the Nrf2/ROS/Bax signalling pathway

We explored how tabersonine (Tab) protected against dexamethasone (Dex)-induced osteoporosis. Osteoblasts were treated with Dex (100 µM) with or without Table (5 or 10 µM). We measured cell viability, alkaline phosphatase (ALP) activity, and mitochondrial superoxide and reactive oxygen species level...

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Bibliografiske detaljer
Udgivet i:AMB Express
Main Authors: Sun, Xi, Gan, Lijun, Li, Nan, Sun, Shuyi, Li, Na
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2020
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486361/
https://ncbi.nlm.nih.gov/pubmed/32915329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-01098-0
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