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Effects of irisin on osteoblast apoptosis and osteoporosis in postmenopausal osteoporosis rats through upregulating Nrf2 and inhibiting NLRP3 inflammasome

The nuclear factor E2-related factor 2 (Nrf2)/NLR family, pyrin domain containing protein 3 (NLRP3) plays an important role in osteoporosis (OP), so the effects of irisin on postmenopausal OP rats and osteoblast apoptosis through Nrf2/NLRP3 were explored in the present study. A total of 45 specific...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Exp Ther Med
Hauptverfasser: Xu, Lili, Shen, Liyan, Yu, Xiaolong, Li, Peng, Wang, Qing, Li, Chengqian
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966163/
https://ncbi.nlm.nih.gov/pubmed/32010273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2019.8313
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