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Tabersonine ameliorates osteoblast apoptosis in rats with dexamethasone-induced osteoporosis by regulating the Nrf2/ROS/Bax signalling pathway

We explored how tabersonine (Tab) protected against dexamethasone (Dex)-induced osteoporosis. Osteoblasts were treated with Dex (100 µM) with or without Table (5 or 10 µM). We measured cell viability, alkaline phosphatase (ALP) activity, and mitochondrial superoxide and reactive oxygen species level...

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Detalhes bibliográficos
Publicado no:AMB Express
Main Authors: Sun, Xi, Gan, Lijun, Li, Nan, Sun, Shuyi, Li, Na
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486361/
https://ncbi.nlm.nih.gov/pubmed/32915329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13568-020-01098-0
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