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MicroRNA-200a activates Nrf2 signaling to protect osteoblasts from dexamethasone
Treatment with dexamethasone in human osteoblasts leads to oxidative stress and cell injures. NF-E2-related factor 2 (Nrf2) is a key anti-oxidant signaling. We want to induce Nrf2 activation via microRNA-mediated silencing its suppressor Keap1. Our results show that microRNA-200a (“miR-200a”) expres...
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| Foilsithe in: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Impact Journals LLC
2017
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5739606/ https://ncbi.nlm.nih.gov/pubmed/29285219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20452 |
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