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Activation of Nrf2 by MIND4-17 protects osteoblasts from hydrogen peroxide-induced oxidative stress

MIND4-17 is a recently developed NF-E2-related factor 2 (Nrf2) activator, which uniquely causes Nrf2 disassociation from Keap1. Here, we showed that pretreatment with MIND4-17 significantly inhibited hydrogen peroxide (H(2)O(2))-induced viability reduction of primary osteoblasts and OB-6 osteoblasti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Guo, Shiguang, Fei, Hao-Dong, Ji, Feng, Chen, Feng-Li, Xie, Yue, Wang, Shou-Guo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739668/
https://ncbi.nlm.nih.gov/pubmed/29285281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22360
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