microRNA-19a protects osteoblasts from dexamethasone via targeting TSC1

Activation of mTOR complex 1 (mTORC1) could protect human osteoblasts from dexamethasone. Tuberous sclerosis complex 1 (TSC1) is mTORC1 upstream inhibitory protein. We demonstrate here that microRNA-19a (“miR-19a”, -3p) targets the 3' untranslated regions of TSC1 mRNA. Expression of miR-19a dow...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Liu, Gang, Chen, Feng-Li, Ji, Feng, Fei, Hao-Dong, Xie, Yue, Wang, Shou-Guo
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788617/
https://ncbi.nlm.nih.gov/pubmed/29416749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23326
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