microRNA-25 targets PKCζ and protects osteoblastic cells from dexamethasone via activating AMPK signaling

AMP-activated protein kinase (AMPK) activation could protect osteoblasts from dexamethasone (Dex). This study aims to provoke AMPK activation via microRNA downregulation of its negative regulator protein kinase C ζ (PKCζ). Results show that microRNA-25-5p (miR-25-5p) targets PKCζ's 3’ untransla...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Fan, Jian-bo, Liu, Wei, Zhu, Xin-hui, Yi, Hong, Cui, Sheng-yu, Zhao, Jian-ning, Cui, Zhi-ming
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356877/
https://ncbi.nlm.nih.gov/pubmed/27911275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13698
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