miR-135b expression downregulates Ppm1e to activate AMPK signaling and protect osteoblastic cells from dexamethasone

Activation of AMP-activated protein kinase (AMPK) could potently protect osteoblasts/osteoblastic cells from dexamethasone (Dex). We aim to induce AMPK activation via microRNA (“miRNA”) downregulation of its phosphatase Ppm1e. We discovered that microRNA-135b (“miR-135b”) targets the 3' untrans...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Fan, Jian-Bo, Ruan, Jian-Wei, Liu, Wei, Zhu, Lun-Qing, Zhu, Xin-Hui, Yi, Hong, Cui, Sheng-Yu, Zhao, Jian-Ning, Cui, Zhi-Ming
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2016
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342578/
https://ncbi.nlm.nih.gov/pubmed/27661114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12138
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