OSU53 Rescues Human OB-6 Osteoblastic Cells from Dexamethasone through Activating AMPK Signaling

Excessive dexamethasone (Dex) application causes osteoblast cell death, which could lead to osteoporosis or osteonecrosis. AMP-activated protein kinase (AMPK) activation is shown to protect osteoblasts/osteoblastic cells from Dex. In this report, we tested the potential effect of OSU53, a novel AMPK...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Xu, Dawei, Zhao, Wei, Zhu, Xinhui, Fan, Jianbo, Cui, Shengyu, Sun, Yuyu, Chen, Xiang, Liu, Wei, Cui, Zhi-ming
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025189/
https://ncbi.nlm.nih.gov/pubmed/27632213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162694
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