Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing

Cellular reprogramming suffers from low efficiency especially for the human cells. To deconstruct the heterogeneity and unravel the mechanisms for successful reprogramming, we adopted single-cell RNA sequencing (scRNA-Seq) and single-cell assay for transposase-accessible chromatin (scATAC-Seq) to pr...

詳細記述

保存先:
書誌詳細
出版年:Sci Adv
主要な著者: Xing, Q. R., El Farran, C. A., Gautam, P., Chuah, Y. S., Warrier, T., Toh, C. X. D., Kang, N. Y., Sugii, S., Chang, Y. T., Xu, J., Collins, J. J., Daley, G. Q., Li, H., Zhang, L. F., Loh, Y. H.
フォーマット: Artigo
言語:Inglês
出版事項: American Association for the Advancement of Science 2020
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486102/
https://ncbi.nlm.nih.gov/pubmed/32917699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba1190
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