Diversification of reprogramming trajectories revealed by parallel single-cell transcriptome and chromatin accessibility sequencing

Cellular reprogramming suffers from low efficiency especially for the human cells. To deconstruct the heterogeneity and unravel the mechanisms for successful reprogramming, we adopted single-cell RNA sequencing (scRNA-Seq) and single-cell assay for transposase-accessible chromatin (scATAC-Seq) to pr...

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Bibliografski detalji
Izdano u:Sci Adv
Glavni autori: Xing, Q. R., El Farran, C. A., Gautam, P., Chuah, Y. S., Warrier, T., Toh, C. X. D., Kang, N. Y., Sugii, S., Chang, Y. T., Xu, J., Collins, J. J., Daley, G. Q., Li, H., Zhang, L. F., Loh, Y. H.
Format: Artigo
Jezik:Inglês
Izdano: American Association for the Advancement of Science 2020
Teme:
Research Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486102/
https://ncbi.nlm.nih.gov/pubmed/32917699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aba1190
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