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Monitoring protein-metal binding by (19)F NMR – a case study with the New Delhi metallo-β-lactamase 1

(19)F NMR protein observed spectroscopy is evaluated as a method for analysing protein metal binding using the New Delhi metallo-β-lactamase 1. The results imply (19)F NMR is useful for analysis of different metallated protein states and investigations on equilibrium states in the presence of inhibi...

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Publicat a:RSC Med Chem
Autors principals: Rydzik, Anna M., Brem, Jürgen, Chandler, Shane A., Benesch, Justin L. P., Claridge, Timothy D. W., Schofield, Christopher J.
Format: Artigo
Idioma:Inglês
Publicat: Royal Society of Chemistry 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484990/
https://ncbi.nlm.nih.gov/pubmed/33479644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00416e
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