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Acidic Submucosal Gland pH and Elevated Protein Concentration Produce Abnormal Cystic Fibrosis Mucus
In response to respiratory insults, airway submucosal glands secrete copious mucus strands to increase mucociliary clearance and protect the lung. However, in cystic fibrosis, stimulating submucosal glands has the opposite effect, disrupting mucociliary transport. In CF pigs, loss of CFTR anion chan...
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| Pubblicato in: | Dev Cell |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7484121/ https://ncbi.nlm.nih.gov/pubmed/32730755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2020.07.002 |
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