Pathological Mucus and Impaired Mucus Clearance in Cystic Fibrosis Patients Results from Increased Concentration, not altered pH

Cystic fibrosis (CF) is a recessive genetic disease that is characterized by airway mucus plugging and reduced mucus clearance. There are currently alternative hypotheses that attempt to describe the abnormally viscous and elastic mucus that is a hallmark of CF airways disease, including: a) loss of...

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Detalhes bibliográficos
Publicado no:Eur Respir J
Main Authors: Hill, David B, Long, Robert F., Kissner, William J, Atieh, Eyad, Garbarine, Ian C, Markovetz, Matthew R, Fontana, Nicholas C, Christy, Matthew, Habibpour, Mehdi, Tarran, Robert, Forest, M Gregory, Boucher, Richard C, Button, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6446239/
https://ncbi.nlm.nih.gov/pubmed/30361244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/13993003.01297-2018
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