Načítá se...

Antibody Probes of Module 1 of the 6-Deoxyerythronolide B Synthase Reveal an Extended Conformation During Ketoreduction

The 6-deoxyerythronolide B synthase (DEBS) is a prototypical assembly-line polyketide synthase (PKS) that synthesizes the macrocyclic core of the antibiotic erythromycin. Each of its six multidomain modules presumably sample distinct conformations, as biosynthetic intermediates tethered to their acy...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Am Chem Soc
Hlavní autoři: Cogan, Dillon P., Li, Xiuyuan, Sevillano, Natalia, Mathews, Irimpan I., Matsui, Tsutomu, Craik, Charles S., Khosla, Chaitan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7484051/
https://ncbi.nlm.nih.gov/pubmed/32786753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c05133
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!