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Roles for the DNA-PK complex and 53BP1 in protecting ends from resection during DNA double-strand break repair
p53-binding protein 1 (53BP1) exerts distinct impacts in different situations involving DNA double-strand break (DSB) rejoining. Here we focus on how 53BP1 impacts upon the repair of ionising radiation-induced DSBs (IR-DSBs) and how it interfaces with Ku, the DNA end-binding component of canonical n...
Enregistré dans:
| Publié dans: | J Radiat Res |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7482155/ https://ncbi.nlm.nih.gov/pubmed/32779701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rraa053 |
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