ロード中...

RECQL4 promotes DNA end resection in repair of DNA double-strand breaks

The RecQ helicase RECQL4, mutated in Rothmund-Thomson syndrome, regulates genome stability, aging and cancer. Here, we identify a crucial role for RECQL4 in DNA end resection, which is the initial and an essential step of homologous recombination (HR)-dependent DNA double-strand break repair (DSBR)....

詳細記述

保存先:
書誌詳細
出版年:Cell Rep
主要な著者: Lu, Huiming, Shamanna, Raghavendra A., Keijzers, Guido, Anand, Roopesh, Rasmussen, Lene Juel, Cejka, Petr, Croteau, Deborah L., Bohr, Vilhelm A.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5576896/
https://ncbi.nlm.nih.gov/pubmed/27320928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.05.079
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!