AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma

The phosphatidylinositide-3 kinases and the downstream mediator AKT drive survival and proliferation of multiple myeloma (MM) cells. AKT signaling is active in MM and has pleiotropic effects; however, the key molecular aspects of AKT dependency in MM are not fully clear. Among the various downstream...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Bloedjes, Timon A., de Wilde, Guus, Maas, Chiel, Eldering, Eric, Bende, Richard J., van Noesel, Carel J. M., Pals, Steven T., Spaargaren, Marcel, Guikema, Jeroen E. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479958/
https://ncbi.nlm.nih.gov/pubmed/32898245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2019001393
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados