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Layilin augments integrin activation to promote antitumor immunity
Tumor-infiltrating CD8(+) T cells mediate antitumor immune responses. However, the mechanisms by which T cells remain poised to kill cancer cells despite expressing high levels of inhibitory receptors are unknown. Here, we report that layilin, a C-type lectin domain–containing membrane glycoprotein,...
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| Publicado no: | J Exp Med |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7478725/ https://ncbi.nlm.nih.gov/pubmed/32539073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192080 |
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