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Selective in vitro anti-cancer activity of non-alkylating minor groove binders
Traditional cytotoxic agents which act through a DNA-alkylating mechanism are relatively non-specific, resulting in a small therapeutic window and thus limiting their effectiveness. In this study, we evaluate a panel of 24 non-alkylating Strathclyde Minor Groove Binders (S-MGBs), including 14 novel...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Medchemcomm |
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| Κύριοι συγγραφείς: | , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Royal Society of Chemistry
2019
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7478159/ https://ncbi.nlm.nih.gov/pubmed/32952999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9md00268e |
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