טוען...
Ranking Ligand Affinity for the DNA Minor Groove by Experiment and Simulation
[Image: see text] The structural and thermodynamic basis for the strength and selectivity of the interactions of minor groove binders (MGBs) with DNA is not fully understood. In 2003, we reported the first example of a thiazole-containing MGB that bound in a phase-shifted pattern that spanned six ba...
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| Main Authors: | , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical Society
2010
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4007966/ https://ncbi.nlm.nih.gov/pubmed/24900221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100047n |
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