Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy

OBJECTIVES: The slow development of major advances in drug discovery for the treatment of Mycobacterium tuberculosis (Mtb) infection suggests a compelling need for evaluation of more effective drug therapies against TB. New classes of drugs are constantly being evaluated for anti-mycobacterial activ...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Hlaka, Lerato, Rosslee, Michael-Jon, Ozturk, Mumin, Kumar, Santosh, Parihar, Suraj P, Brombacher, Frank, Khalaf, Abedawn I, Carter, Katharine C, Scott, Fraser J, Suckling, Colin J, Guler, Reto
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890746/
https://ncbi.nlm.nih.gov/pubmed/28961913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx326
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