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Topical Simvastatin as Host-Directed Therapy against Severity of Cutaneous Leishmaniasis in Mice
We recently demonstrated that statins mediate protection against intracellular pathogens, Mycobacterium tuberculosis and Listeria monocytogenes in mice. Here, we investigated the immunomodulatory potential of simvastatin as a topical or systemic host-directed drug therapy in controlling inflammatory...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5025842/ https://ncbi.nlm.nih.gov/pubmed/27632901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33458 |
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