Topical Simvastatin as Host-Directed Therapy against Severity of Cutaneous Leishmaniasis in Mice

We recently demonstrated that statins mediate protection against intracellular pathogens, Mycobacterium tuberculosis and Listeria monocytogenes in mice. Here, we investigated the immunomodulatory potential of simvastatin as a topical or systemic host-directed drug therapy in controlling inflammatory...

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Udgivet i:Sci Rep
Main Authors: Parihar, Suraj P., Hartley, Mary-Anne, Hurdayal, Ramona, Guler, Reto, Brombacher, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025842/
https://ncbi.nlm.nih.gov/pubmed/27632901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33458
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