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Simvastatin Enhances Protection against Listeria monocytogenes Infection in Mice by Counteracting Listeria-Induced Phagosomal Escape

Statins are well-known cholesterol lowering drugs targeting HMG-CoA-reductase, reducing the risk of coronary disorders and hypercholesterolemia. Statins are also involved in immunomodulation, which might influence the outcome of bacterial infection. Hence, a possible effect of statin treatment on Li...

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Bibliografiske detaljer
Main Authors: Parihar, Suraj P., Guler, Reto, Lang, Dirk M., Suzuki, Harukazu, Marais, A. David, Brombacher, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782446/
https://ncbi.nlm.nih.gov/pubmed/24086542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075490
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