Decitabine and Vorinostat with Chemotherapy in Relapsed Pediatric Acute Lymphoblastic Leukemia: A TACL Pilot Study

PURPOSE: Treatment failure from drug resistance is the primary reason for relapse in acute lymphoblastic leukemia. Improving outcomes by targeting mechanisms of drug resistance is a potential solution. EXPERIMENTAL DESIGN: We report results investigating the epigenetic modulators decitabine and vori...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Clin Cancer Res
Κύριοι συγγραφείς: Burke, Michael J., Kostadinov, Rumen, Sposto, Richard, Gore, Lia, Kelley, Shannon, Rabik, Cara, Trepel, Jane, Lee, Min-Jung, Yuno, Akira, Lee, Sunmin, Bhojwani, Deepa, Jeha, Sima C., Chang, Bill H., Sulis, Maria Luisa, Hermiston, Michelle L., Gaynon, Paul S., Huynh, Van, Verma, Anupam, Gardner, Rebecca A., Heym, Kenneth M., Dennis, Robyn M., Ziegler, David S., Laetsch, Theodore W., Oesterheld, Javier E., DuBois, Steven G., Pollard, Jessica A., Glade-Bender, Julia, Cooper, Todd M., Kaplan, Joel A., Farooqi, Midhat, Yoo, Byunggil, Guest, Erin, Wayne, Alan S., Brown, Patrick
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2020
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7477726/
https://ncbi.nlm.nih.gov/pubmed/31969338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-19-1251
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