Phase I study of decitabine in combination with vorinostat in patients with advanced solid tumors and non-Hodgkin's lymphomas

PURPOSE: This phase I study evaluated the safety, tolerability, pharmacokinetics and preliminary efficacy of the combination of decitabine with vorinostat. PATIENTS AND METHODS: Patients with advanced solid tumors or non-Hodgkin's lymphomas were eligible. Sequential and concurrent schedules wer...

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Autori principali: Stathis, Anastasios, Hotte, Sebastien J., Chen, Eric X., Hirte, Holger W., Oza, Amit M., Moretto, Patricia, Webster, Sheila, Laughlin, Anne, Stayner, Lee-Anne, McGill, Shauna, Wang, Lisa, Zhang, Wen-jiang, Espinoza-Delgado, Igor, Holleran, Julianne L., Egorin, Merrill J., Siu, Lillian L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997755/
https://ncbi.nlm.nih.gov/pubmed/21152384
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