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The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase
Efficient search for DNA damage embedded in vast expanses of the DNA genome presents one of the greatest challenges to DNA repair enzymes. We report here crystal structures of human 8-oxoguanine (oxoG) DNA glycosylase, hOGG1, that interact with the DNA containing the damaged base oxoG and the normal...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7477556/ https://ncbi.nlm.nih.gov/pubmed/32895378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18290-2 |
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