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8-Oxoguanine DNA Glycosylases: One Lesion, Three Subfamilies
Amongst the four bases that form DNA, guanine is the most susceptible to oxidation, and its oxidation product, 7,8-dihydro-8-oxoguanine (8-oxoG) is the most prevalent base lesion found in DNA. Fortunately, throughout evolution cells have developed repair mechanisms, such as the 8-oxoguanine DNA glyc...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Molecular Diversity Preservation International (MDPI)
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3397491/ https://ncbi.nlm.nih.gov/pubmed/22837659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13066711 |
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