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8-Oxoguanine DNA Glycosylases: One Lesion, Three Subfamilies

Amongst the four bases that form DNA, guanine is the most susceptible to oxidation, and its oxidation product, 7,8-dihydro-8-oxoguanine (8-oxoG) is the most prevalent base lesion found in DNA. Fortunately, throughout evolution cells have developed repair mechanisms, such as the 8-oxoguanine DNA glyc...

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Bibliografiska uppgifter
Huvudupphovsmän: Faucher, Frédérick, Doublié, Sylvie, Jia, Zongchao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Molecular Diversity Preservation International (MDPI) 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397491/
https://ncbi.nlm.nih.gov/pubmed/22837659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms13066711
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