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The C-terminal lysine of Ogg2 DNA glycosylases is a major molecular determinant for guanine/8-oxoguanine distinction
7,8-dihydro-8-oxoguanine (8-oxoG) is a major oxidative lesion found in DNA. The 8-oxoguanine DNA glycosylases (Ogg) responsible for the removal of 8-oxoG are divided into three families: Ogg1, Ogg2 and AGOG. Since Ogg2 members are devoid of the recognition loop used by Ogg1 to discriminate between 8...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3085930/ https://ncbi.nlm.nih.gov/pubmed/20083120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.024 |
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