Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

OBJECTIVE: To identify additional genetic variants beyond those observed in a previous genome-wide association study (GWAS) in women treated on the MA.27 clinical trial in which women were randomized to 5 years of adjuvant therapy with anastrozole or exemestane. PATIENTS AND METHODS: We performed a...

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Udgivet i:Pharmacogenet Genomics
Main Authors: Ingle, James N., Kalari, Krishna R., Momozawa, Yukihide, Kubo, Michiaki, Furukawa, Yoichi, Shepherd, Lois E., Ellis, Matthew J., Goss, Paul E., Barman, Poulami, Carlson, Erin E., Sinnwell, Jason P., Tang, Xiaojia, Goetz, Matthew P., Chen, Bingshu E., Cairns, Junmei, Weinshilboum, Richard M., Wang, Liewei
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7474544/
https://ncbi.nlm.nih.gov/pubmed/31211741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0000000000000382
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