Genetic polymorphisms in the long noncoding RNA MIR2052HG offer a pharmacogenomic basis for the response of breast cancer patients to aromatase inhibitor therapy

Genetic risks in breast cancer remain only partly understood. Here we report the results of a genome-wide association study of germline DNA from 4,658 women, including 252 women experiencing a breast cancer recurrence, who were entered on the MA.27 adjuvant trial comparing the aromatase inhibitors (...

詳細記述

保存先:
書誌詳細
出版年:Cancer Res
主要な著者: Ingle, James N., Xie, Fang, Ellis, Matthew J., Goss, Paul E., Shepherd, Lois E., Chapman, Judith-Anne W., Chen, Bingshu E., Kubo, Michiaki, Furukawa, Yoichi, Momozawa, Yukihide, Stearns, Vered, Pritchard, Kathleen I., Barman, Poulami, Carlson, Erin E., Goetz, Matthew P., Weinshilboum, Richard M., Kalari, Krishna R., Wang, Liewei
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5135610/
https://ncbi.nlm.nih.gov/pubmed/27758888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1371
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