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High-throughput methods for measuring DNA thermodynamics

Understanding the thermodynamics of DNA motifs is important for prediction and design of probes and primers, but melt curve analyses are low-throughput and produce inaccurate results for motifs such as bulges and mismatches. Here, we developed a new, accurate and high-throughput method for measuring...

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Dettagli Bibliografici
Pubblicato in:Nucleic Acids Res
Autori principali: Bae, Jin H, Fang, John Z, Zhang, David Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470960/
https://ncbi.nlm.nih.gov/pubmed/32544247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa521
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