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A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis
Cellular genomes are constantly damaged by endogenous and exogenous agents that covalently and structurally modify DNA to produce DNA lesions. Although most lesions are mended by various DNA repair pathways in vivo, a significant number of damage sites persist during genomic replication. Our underst...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3632128/ https://ncbi.nlm.nih.gov/pubmed/23470999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt141 |
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