A high-throughput and quantitative method to assess the mutagenic potential of translesion DNA synthesis

Cellular genomes are constantly damaged by endogenous and exogenous agents that covalently and structurally modify DNA to produce DNA lesions. Although most lesions are mended by various DNA repair pathways in vivo, a significant number of damage sites persist during genomic replication. Our underst...

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Detalhes bibliográficos
Main Authors: Taggart, David J., Camerlengo, Terry L., Harrison, Jason K., Sherrer, Shanen M., Kshetry, Ajay K., Taylor, John-Stephen, Huang, Kun, Suo, Zucai
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3632128/
https://ncbi.nlm.nih.gov/pubmed/23470999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt141
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