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Angiogenin and tRNA fragments in Parkinson’s disease and neurodegeneration

In this review, we summarise the evidence for a role of the ribonuclease angiogenin in the pathophysiology of neurodegenerative disorders, with a specific focus on Parkinson’s disease (PD). Angiogenin is a stress-induced, secreted ribonuclease with both nuclear and cytosolic activities. Loss-of-func...

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Dades bibliogràfiques
Publicat a:Acta Pharmacol Sin
Autors principals: Prehn, Jochen H M, Jirström, Elisabeth
Format: Artigo
Idioma:Inglês
Publicat: Springer Singapore 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470775/
https://ncbi.nlm.nih.gov/pubmed/32144338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0375-9
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