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Angiogenin-induced tRNA fragments inhibit translation initiation
Angiogenin is a stress-activated ribonuclease that cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs). Transfection of natural or synthetic tiRNAs inhibits protein synthesis and triggers the phospho-eIF2α independent assembly of stress granules (SGs), essen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3160621/ https://ncbi.nlm.nih.gov/pubmed/21855800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.022 |
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