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Angiogenin-induced tRNA fragments inhibit translation initiation

Angiogenin is a stress-activated ribonuclease that cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs). Transfection of natural or synthetic tiRNAs inhibits protein synthesis and triggers the phospho-eIF2α independent assembly of stress granules (SGs), essen...

詳細記述

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書誌詳細
主要な著者: Ivanov, Pavel, Emara, Mohamed M., Villen, Judit, Gygi, Steven P., Anderson, Paul
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3160621/
https://ncbi.nlm.nih.gov/pubmed/21855800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.022
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