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Angiogenin cleaves tRNA and promotes stress-induced translational repression
Stress-induced phosphorylation of eIF2α inhibits global protein synthesis to conserve energy for repair of stress-induced damage. Stress-induced translational arrest is observed in cells expressing a nonphosphorylatable eIF2α mutant (S51A), which indicates the existence of an alternative pathway of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700517/ https://ncbi.nlm.nih.gov/pubmed/19332886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200811106 |
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