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Angiogenin cleaves tRNA and promotes stress-induced translational repression

Stress-induced phosphorylation of eIF2α inhibits global protein synthesis to conserve energy for repair of stress-induced damage. Stress-induced translational arrest is observed in cells expressing a nonphosphorylatable eIF2α mutant (S51A), which indicates the existence of an alternative pathway of...

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Hlavní autoři: Yamasaki, Satoshi, Ivanov, Pavel, Hu, Guo-fu, Anderson, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2700517/
https://ncbi.nlm.nih.gov/pubmed/19332886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200811106
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