Genome-wide Identification and Quantitative Analysis of Cleaved tRNA Fragments Induced by Cellular Stress

Certain stress conditions can induce cleavage of tRNAs around the anticodon loop via the use of the ribonuclease angiogenin. The cellular factors that regulate tRNA cleavage are not well known. In this study we used normal and eIF2α phosphorylation-deficient mouse embryonic fibroblasts and applied a...

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Main Authors: Saikia, Mridusmita, Krokowski, Dawid, Guan, Bo-Jhih, Ivanov, Pavel, Parisien, Marc, Hu, Guo-fu, Anderson, Paul, Pan, Tao, Hatzoglou, Maria
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2012
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3522271/
https://ncbi.nlm.nih.gov/pubmed/23086926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.371799
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