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The Many Virtues of tRNA-derived Stress-induced RNAs (tiRNAs): Discovering Novel Mechanisms of Stress Response and Effect on Human Health
In mammalian cells, mature tRNAs are cleaved by stress-activated ribonuclease angiogenin to generate 5′- and 3′-tRNA halves: a novel class of small non-coding RNAs of 30–40 nucleotides in length. The biogenesis and biological functions of tRNA halves are emerging areas of research. This review will...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705977/ https://ncbi.nlm.nih.gov/pubmed/26463210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R115.694661 |
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