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Angiogenin and tRNA fragments in Parkinson’s disease and neurodegeneration

In this review, we summarise the evidence for a role of the ribonuclease angiogenin in the pathophysiology of neurodegenerative disorders, with a specific focus on Parkinson’s disease (PD). Angiogenin is a stress-induced, secreted ribonuclease with both nuclear and cytosolic activities. Loss-of-func...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Prehn, Jochen H M, Jirström, Elisabeth
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Singapore 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470775/
https://ncbi.nlm.nih.gov/pubmed/32144338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41401-020-0375-9
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