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Cell wall inhibitors increase the accumulation of rifampicin in Mycobacterium tuberculosis

There is a need for new combination regimens for tuberculosis. Identifying synergistic drug combinations can avoid toxic side effects and reduce treatment times. Using a fluorescent rifampicin conjugate, we demonstrated that synergy between cell wall inhibitors and rifampicin was associated with inc...

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Publicado en:Access Microbiol
Autores principales: McNeil, Matthew B., Chettiar, Somsundaram, Awasthi, Divya, Parish, Tanya
Formato: Artigo
Lenguaje:Inglês
Publicado: Microbiology Society 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7470358/
https://ncbi.nlm.nih.gov/pubmed/32974492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/acmi.0.000006
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