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Deletion of cyp125 Confers Increased Sensitivity to Azoles in Mycobacterium tuberculosis
Mycobacterium tuberculosis is able to utilize cholesterol as a carbon source, and this ability is linked to its virulence in macrophages and in the mouse model of infection. The M. tuberculosis cytochrome P450 Cyp125 plays a key role in cholesterol metabolism being involved in the first steps of its...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4510303/ https://ncbi.nlm.nih.gov/pubmed/26197389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133129 |
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