Report of the use of patient‐derived xenograft models in the development of anticancer drugs in Japan

Cell line‐derived xenograft (CDX) models created by implanting cancer cell lines into immunodeficient mice have contributed largely to the development of cancer drug therapies. However, cell lines often lose their original biological characteristics through many passages and cancer tissues in CDX mo...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Tsumura, Ryo, Koga, Yoshikatsu, Hamada, Akinobu, Kuwata, Takeshi, Sasaki, Hiroki, Doi, Toshihiko, Aikawa, Katsuji, Ohashi, Akihiro, Katano, Ikumi, Ikarashi, Yoshinori, Ito, Mamoru, Ochiai, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
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Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7469811/
https://ncbi.nlm.nih.gov/pubmed/32639672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14564
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